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mesothelial cyst pathology outlines I Mesothelial cysts - Pathology Outlines

mesothelial cyst pathology outlines I Mesothelial cysts - Pathology Outlines

Kidney nontumor

Developmental & cystic diseases

Mesothelial cysts

Author: Mandolin S. Ziadie, M.D.

Topic Completed: 1 December 2011

Minor changes: 11 March 2021

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Mesothelial cysts kidney

Mandolin S. Ziadie, M.D.

Cite this page: Ziadie MS. Mesothelial cysts. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/kidneytumormesothelialcyst.html. Accessed May 22nd, 2021.

Definition / general
Rare; cysts lined by mesothelial cells in vicinity of kidney that may present as renal masses
Also called primary retroperitoneal cysts of mesothelial origin

Gross description
Thin walled, unilocular cyst filled with clear fluid
May be hemorrhagic

Microscopic (histologic) description
Thin walled cyst lined by single cell lining of nonpleomorphic cells with abundant eosinophilic cytoplasm, vesicular nuclei and small nucleoli
May have small gland-like spaces

Positive stains
Alcian blue, keratin, vimentin, HBME1, WT1, thrombomodulin and calretinin

Negative stains
BerEP4, CEA, B72.3 and LeuM1

Differential diagnosis
Lymphangioma: multicystic, has smooth muscle and lymphocytes in cyst wall and lumen, keratin+

Mucinous cystadenoma: ovarian-like stroma, mucin+, CEA+, negative for hyaluronic acid
Simple hemorrhagic cyst

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